iNEXT is a consortium funded by the Horizon2020 program to offer European researchers access to a wide range of advanced structural biology technologies, including X-ray technologies, NMR spectroscopy, Electron Microscopy and Biophysics, in large European infrastructures.
iNEXT offers access to infrastructures to study the structure and function of biological macromolecules and their assemblies, and aspires to promote biomedicine, biotechnology, and biomaterials, involving scientists with or without previous experience in structural biology.
iNEXT follows the revolution in cryo-electron microscopy, offering for the first time trans-national access to high-end transmission electron microscopes. Access to biophysics facilities to study macromolecular interactions in cells and in vivo, is also offered for the first time.
iNEXT has ended. To request access to European structural biology facilities, we encourage all former iNEXT users to get in touch with the iNEXT-Discovery project.
The iNEXT-Discovery partnership, a renewed team from the one that conceived, organised and successfully run the iNEXT consortium, brings together facilities for X-rays, NMR, cryo-EM and macromolecular biophysics, and aims to make them accessible to new user communities, develop the methods further through joined research efforts, and offer better integration between scientific fields and within the field of structural biology, through scientific meetings, practical courses, and training workshops.
The iNEXT project has resulted in more than 200 scientific publications. A list of all our publications can be found on our publication page.
iNEXT ran until September 2019 and supported researchers from all EU and associated countries, but also (in a more limited capacity) from international labs, to perform a variety of Structural Biology experiments with a translational research component, in the fields of X-ray crystallography, SAXS, NMR, EM, light imaging and Biophysics for Macromolecular Interactions. Support included all access costs to all facilities, and support for travel and accommodation for the duration of experiments, where applicable. We particularly encouraged applications from people with no or limited experience to the different techniques to look at our Extended Support and Structural Audit modalities, as well as expert researchers that will be more interested in our High-End Data collection modalities.
The iNEXT consortium involved 23 partners from 14 different European countries. Training and networking activities were carried out to attract new users and to disseminate scientific results across academia and industry.