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  • Integrating infrastructures for Structural Biology

    iNEXT is a consortium funded by the Horizon2020 program to offer European researchers access to a wide range of advanced structural biology technologies, including X-ray technologies, NMR spectroscopy, Electron Microscopy and Biophysics, in large European infrastructures.

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  • Transnational Access to European Infrastructures

    iNEXT offers access to infrastructures to study the structure and function of biological macromolecules and their assemblies, and aspires to promote biomedicine, biotechnology, and biomaterials, involving scientists with or without previous experience in structural biology.

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  • New Methods in Trans-national Access

    iNEXT follows the revolution in cryo-electron microscopy, offering for the first time trans-national access to high-end transmission electron microscopes. Access to biophysics facilities to study macromolecular interactions in cells and in vivo, is also offered for the first time.

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iNEXT: Infrastructure for NMR, EM and X-rays for Translational Research

Upcoming events

  • Mon
    13
    May
    2019
    Fri
    17
    May
    2019

    iNEXT course: X-ray and neutron crystallography: from data collection to structures

    Oulu, Finland
  • Wed
    22
    May
    2019
    Fri
    24
    May
    2019

    Instruct Biennial Structural Biology Conference

    Alcala de Henares, Madrid, Spain
  • Wed
    29
    May
    2019
    Fri
    31
    May
    2019

    Integrated methodologies and approaches for structural biology

    Masaryk University, Campus Bohunice, Brno Czech Republic
  • Wed
    26
    Jun
    2019
    Fri
    28
    Jun
    2019

    4th Annual User Meeting of iNEXT

    Lund, Sweden
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Publications

146. Holm et al., J Biol Chem (2018)

“Biochemical and structural studies reveal differences and commonalities among cap-snatching endonucleases from segmented negative-strand RNA viruses”. Holm T, Kopicki JD, Busch C,...

145. Berbeć et al., J Phys Chem B (2018)

“β2-Type Amyloidlike Fibrils of Poly-l-glutamic Acid Convert into Long, Highly Ordered Helices upon Dissolution in Dimethyl Sulfoxide”. Berbeć S, Dec R, Molodenskiy D, Wielgus-Kutrowska...

144. Marra et al., Chemistry (2018)

“Protein Glycosylation through Sulfur Fluoride Exchange (SuFEx) Chemistry: The Key Role of a Fluorosulfate Thiolactoside.”. Marra A, Dong J, Ma T, Giuntini S, Crescenzo E, Cerofolini L,...

143. Böttcher and Nassal, Journal of Molecular Biology (2018)

“Structure of Mutant Hepatitis B Core Protein Capsids with Premature Secretion Phenotype”. Böttcher B, Nassal M. J Mol Biol. 2018 Dec 7;430(24):4941-4954. doi: 10.1016/j.jmb.2018.10.018....
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News

26th Mar 2019
Announcement

4th iNEXT Annual User Meeting – 26-28 June 2019 – Lund, Sweden

The fourth and final Annual User meeting of iNEXT will take place from 26-28 June 2019 in Lund, Sweden. The meeting aims at gathering all iNEXT Partners, but also inviting guests of the facilities involved in the project. iNEXT Partners, together with members of the Scientific Advisory Board, the...
25th Feb 2019
Announcement

iNEXT Course “X-ray and neutron crystallography: from data collection to structures”: Registration is open!

We are pleased to announce the iNEXT course: “X-ray and neutron crystallography: from data collection to structures”. This intensive course is organized from May-13 to May-17, 2019 at Biocenter Oulu and at the Faculty of Biochemistry and Molecular Medicine, University of Oulu in Oulu, Finland....
24th Jan 2019
Announcement

4th Instruct Biennial Structural Biology Conference: Registration is open!

Instruct-ERIC is a distributed European Research Infrastructure, which provides scientists with access to all major cutting edge technologies that enable biomacromolecular structure determination at atomic resolution. Access to all of these technologies has been available to European member...
10th Jan 2019
Announcement

iNEXT Workshop on integrated structural biology: Registration is open!

The iNEXT workshop “Integrated methodologies and approaches for structural biology” will be held in Brno (Czech republic). The aim of this workshop is to provide a comprehensive overview of the state-of-the-art progress of integrative methodologies to existing and potential users of...

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  Join our network

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iNEXT for you!

iNEXT can support researchers from all EU and associated countries, but also (in a more limited capacity) from international labs, to perform a variety of Structural Biology experiments with a translational research component, in the fields of X-ray crystallography, SAXS, NMR, EM, light imaging and Biophysics for Macromolecular Interactions. Support includes all access costs to all facilities, and support for travel and accommodation for the duration of experiments, where applicable. We particularly encourage applications from people with no or limited experience to the different techniques to look at our Extended Support and Structural Audit modalities, as well as expert researchers that will be more interested in our High-End Data collection modalities.

Submission of proposals

We welcome proposals that aim to advance science in Biomedicine, Biotechnology, and Biomaterials by providing new knowledge about structure and function of biological macromolecules and their assemblies.

Submit Proposal

Europe-wide network


Contact

The iNEXT consortium involves 23 partners from 14 different European countries. Training and networking activities are carried out to attract new users and to disseminate scientific results across academia and industry.

EU funding

Funded from the Horizon 2020 programme of the European Union, iNEXT (H2020 Grant # 653706) is the first research infrastructure project that combines access to different structural biology technologies (SAXS, X-ray crystallography, NMR, EM, biophysical characterization).

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iNEXT Publications 117
Finished Projects 294
Approved Projects 639
Proposals submitted 845
iNEXT users 1182

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For comments and questions please contact us: info@inext-eu.org