- Providing access to state-of-the-art infrastructures for structural biology.
- Use the research infrastructures for translating fundamental research into bio-scientific applications.
- Stimulate access for non-structural biologists.
- Data collection for macromolecular X-ray crystallography, solution scattering (SAXS), Nuclear Magnetic Resonance (NMR), Electron Microscopy (EM) and Advanced Light Microscopy (ALM).
- Show the possibilities offered by the new neutron source: the European Spallation Source (ESS).
- Access is in coordination with Instruct, moving to common access mechanisms and single sign-on.
- Linking in vitro findings for macromolecular assemblies and their interactions to in-cell studies.
- Promoting drug development by enabling ligand fragment screening methods for the discovery of chemical probes and hits.
- Links between industrial and academic structural biologists will be strengthened by collaborative networks, training events, new research opportunities, and by showcasing new technologies.
Three themes of access for experts and non-experts
- Sample quality assessment for non-structural biologists: Structural Audit
- Fully supported access for non-structural biologists: Enhanced Support
- Access for experts to advanced equipment: High-End Data Collection
Joint biomedical research activities to promote integration of the infrastructures and expansion to new communities
- Structure-based small molecule inhibitor discovery (ligand screening).
- Integrated study of membrane proteins.
- Study of macromolecules and their complexes in cells.
- Involving and training new scientific communities and the general public.
- Gateways to industry.
- Strengthening the iNEXT community.
- Data Management and links with e-Infrastructures.
Scientific Advisory Board
- iNEXT’s international Scientific Advisory Board is composed of high profile structural biologists with different scientific background and expertise:
- Bridget Carragher
Director Simons Electron Microscopy Center at New York Structural Biology Center
New York, USA
- Johan Garssen
Professor Immunopharmacology at Utrecht University, Director Platform Immunology at Nutricia Research
Utrecht, The Netherlands
- Astrid Gräslund
Professor of Biophysics at Stockholm University
- Jan Löwe
Deputy Director Medical Research Council – Laboratory of Molecular Biology (MRC-LMB)
Cambridge, United Kingdom
- Ray Stevens
Provost Professor of Biological Sciences and Chemistry at University of Southern California, Director of the Bridge Institute
Los Angeles, USA