Access for “Macromolecular Interactions”

The Macromolecular Interactions access modality is now open for applications! Researchers can apply for a one to two weeks visit at the NKI, to work under expert guidance to setup and performs your experiments characterising macromolecular interactions by biophysical methods. Available methods include surface plasmon resonance, isothermal titration calorimetry, thermal shift assays with and without fluorescent reporter probes, multi-angle laser light scattering, microscale thermophoresis, and various fluorescent modalities (intensity, polarisation, FRET) both in steady state using a state of the art fluorimeter with two injectors and time resolution of a few seconds, but also in transient kinetics setting using a stopped-flow with millisecond resolution.