1. Structural Audit (no previous experience)
This theme includes several novel access modes. These are mail-in services for basic analysis for suitability of samples for structural biology research. The modalities do not include a visit and the analysis is done by local experts.
2. Enhanced Support (non-structural biologists)
Six new modalities have been developed to attract users without previous expertise in structural biology. The modalities in this theme include structural studies by X-ray crystallography, SAXS or NMR, EM sample optimization, ligand and fragment screening, advanced light imaging, and the study of macromolecular interactions in vitro or ex vivo (in cells). This type of access is typically guided by experts from the host institutes and involves training and active participation of visiting users.
3. High-End Data Collection (expert users)
Experienced structural biologists can access synchrotron beamlines, high frequency NMR magnets and state-of-the-art cryo-EM instruments.